Ovarian hyperstimulation syndrome

It is the most important complication of ovarian stimulation treatments used in the ovariana.El stimulation techniques are characterized by the ovaries increase in size due to increased vascular permeability.

Grade I (mild hyperstimulation)

  • Abdominal discomfort;
  • Increase in size of ovaries observed ultrasound, diameter up to 5x5cm; multiple follicles and cysts of body yellow;
  • Oestradiol over 3.000pg/ml; over 30pg/ml progesterone in early luteal phase;
  • Urinary estrogen is over 150mg/24 hours pregnanediol over 10mg / 24 hours;

Grade II (moderate hyperstimulation)

  • Abdominal discomfort, abdominal pain, flatulence, nausea, vomiting, diarrhea;
  • Early signs suggestive: Sudden increase in weight over 3 kg;
  • Ovaries appear enlarged on ultrasound examination, up to 12x12cm;
  • Biochemical examinations, blood counts and slightly modified;

Grade III (severe hyperstimulation)

  • Fluid collections in the abdominal or thoracic: ascites, hidrotorace, hidropericard;
  • Marked blood count changes, trombembolie even hypovolemic shock;

Ovary-diameter increase over 12 cm.

It requires careful monitoring of patients with polycystic ovary syndrome who carried out a controlled stimulation.

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