Antiphospholipid antibody syndrome

Clinical Criteria

One or more episodes of arterial, venous or small vessel thrombosis, occurring in any tissue or organ. Complications of pregnancy: one or more unexplained deaths of a morphologically normal fetus more than 10 weeks of gestation documented by ultrasound or by direct examination


One or more preterm births of a morphologically normal neonate at or before 34 weeks or gestation due to severe pre-eclampsia or placental insufficiency.


Three or more consecutive abortions before 10 weeks gestation with no maternal and paternal chromosomes and other causes of recurrent losses being ruled out.

Laboratory Criteria

  1. Anticardiolipin antibodies (aCL): aCL IgM antibodies present in moderate or high titers on 2 or more occasions at least 6 weeks apart.
  2. Lupus anticoagulant: Detection of LA using phospholipids dependent tests for coagulation such as dilute Russel Viper Test (dVRRT), Kaolin clotting time (KCT) and activated partial thromboplastin time (aPTT).

Cabinet Ginecologic

Cabinet Ginecologie / Ecografie 2D, 3D, 4D, Doppler Color
Videocolposcopie / Planificare familiala

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